Current SORCE Projects


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SORCE

While SORCE started in the surgical outcomes research arena, it has grown into a full service administrative hub for multicenter collaborative research and quality improvement at the regional and national level, a learning healthcare system, and a provider of services such as registry building and collaborative development.

Multicenter Collaborative Research

Alliance of Randomized trials of Medicine vs. Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D)
Funder: The Cleveland Clinic Foundation
Four investigative groups from across the nation have pooled results from randomized control trials (RCTs) to evaluate the long-term effectiveness of bariatric surgery compared to multidisciplinary medical and lifestyle management of diabetes and body weight.

Improving Lung Cancer Staging with a Prediction Model and a Biomarker
Funder: CHEST Foundation (American College of Chest Physicians)
This study focuses on the development of a mathematical model to help physicians better utilize information from CAT and PET scans, as well as blood tests, to predict the chances of cancer in mediastinal lymph nodes.

Longitudinal Assessment of Bariatric Surgery Sub-study: Mechanisms of Durability of Type 2 Diabetes Remission (LABS 3)
Funder: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Through Oregon Health and
Science University
This study aims to improve our understanding of the physiological mechanisms leading to diabetes remission after bariatric surgery by comparing and contrasting subjects with and without diabetes pre- and post-gastric bypass surgery in long-term follow-up (five and seven years).

Using Risk-Prediction to Improve Lung Cancer Surveillance
Funder: National Cancer Institute (NCI) through the Fred Hutch / University of Washington Cancer Consortium
In this study, we aim to: I) develop a prediction model using known risk-factors to estimate the probably of lung cancer recurrence; and II) determine whether or not expression patterns of a protein called VEGF-C is associated with a higher risk of lung cancer recurrence.

CERTAIN – Comparative Effectiveness Research Translation Network

CERTAIN is the program at SORCE which serves as WA State’s “learning healthcare system,” a network of diverse healthcare providers and organizations participating in continuous evaluation of healthcare delivery and learning to improve patient care. Current CERTAIN projects include: 

Appendicitis Patient Pre-Hospital Experience (APPE) Survey: Patient Decision-Making in Appendicitis
Funder: University of Washington Department of Surgery

CERTAIN Chronic Conditions
Funder: Agency for Healthcare Research & Quality (AHRQ)

CERTAIN Hub
Funder: Life Sciences Discovery Fund (LSDF)

Collaborating to Promote the Collection and use of Patient Reported Outcomes
Funder: Agency for Healthcare Research and Quality (AHRQ) through the AcademyHealth

Comparing Engagement Techniques for Incorporating Patient Input in Research Prioritization (SMARTER)
Funder: Patient-Centered Outcomes Research Institute (PCORI)

Comparing Outcomes of Drugs and Appendectomy (CODA)
Funder: Patient-Centered Outcomes Research Institute (PCORI)

Developing Design Principles to Integrate PROs into Clinical Practice Through HIT: Data, User Experience, and Workflow Requirements for PRO Dashboards
Funder: Agency for Healthcare Research and Quality (AHRQ)

Extending PROMIS Pain Item Banks: Pain Self-Efficacy and Pain Catastrophizing
Funder: Patient-Centered Outcomes Research Institute (PCORI)

Mobile Strong for Surgery
Funder: Nestlé HealthCare Nutrition, Inc.

mPOWEr: mobile Post-Operative Wound Evaluator
Funder: Surgical Infection Society (SIS)

Patient Voices: Supporting Patient Involvement in the Learning Healthcare System (INSPIRE)
Funder: Patient-Centered Outcomes Research Institute (PCORI)

Practice Patterns and Impact of Operative and Non-operative Management of Diverticulitis (DEBUT)
Funder: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Topical Antibiotic Treatment for Spine Surgical Site Infections
Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Understanding Non-response in Spine Fusion Surgery
Funder: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

For information on each CERTAIN project, visit the website here.

Quality Improvement

National Surgical Quality Improvement Program (NSQIP) and Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP)
NSQIP is a risk-adjusted data collection mechanism that collects and analyzes surgical clinical outcomes data. 

mPOWEr: Piloting a Mobile Health App for Post-Discharge Surgical Site Monitoring
Funder: Patient Safety Innovations Program (PSIP)

This quality improvement initiative works to use mPOWEr, a health information technology (Health IT) app, to improve patient care without added burden to clinical workflow in Burn and Plastic Surgery Clinics at Harborview. For information, visit the website here.

Services

CRN Scholars
SORCE hosts Cancer Research Network (CRN) Scholars sponsored by the National Cancer Institute (NCI).

Former CRN Scholar
Farhood Farjah, MD, MPH

Current CRN Scholar
Sara Javid, MD

OB/GYN Outcomes
Begun in 2014, SORCE and the Department of Obstetrics (OB) and Gynecology (GYN) invested in building an outcomes research program for early-stage OB/GYN researchers. Junior faculty are supported through the development of their research programs with SORCE project leads, analysts, grant writers, and more. We currently have three junior faculty participating in this partnership. Already, this partnership has led to one faculty member applying for and being awarded the opportunity to represent UW on the American Urogynecologic Society Junior Faculty Network.

Collaboratives

CT Health Services and Outcomes Research
Begun in 2012, SORCE and the Division of Cardiothoracic (CT) Surgery invested in building a health services and outcomes research program for cardiothoracic surgery. In addition to the preeminent goals of improving public health and advancing the field of cardiothoracic surgery, this group aims to support faculty career development, train the next generation of clinical scientists, and expand collaborative relationships with other specialties, scientists, and stakeholders in healthcare.

CERTAIN CHOICES
Begun in 2013 and utilizing both the leadership within the Department of Surgery and the CERTAIN platform, the multidisciplinary Collaborative for Healthcare research in behaviOral economIcs and deCision sciEnceS (CERTAIN CHOICES) brings together faculty from UW’s Foster School of Business, the Natural Sciences Division of the College of Arts and Sciences (Department of Psychology), School of Public Health, School of Medicine (Departments of Global Health, Radiology, and Surgery), the College of Engineering (Department of Computer Science & Engineering), and the School of Pharmacy. This multidisciplinary group meets monthly to discuss understanding patient decision making and then improving the way decisions are made. 

INFORM
Begun in 2014, Improving Nursing Facility Outcomes using Real Time Metrics (INFORM) is a collaborative in Washington State that leverages the research infrastructure of CERTAIN to bring together skilled nursing facilities (SNF) practitioners and administrators to examine the factors that improve the care of surgical patients following discharge from the hospital to SNFs. This group meets every three weeks to discuss quality improvement, collect feedback from clinicians and SNFs, and creates benchmarks for improving patient centered standards of care for acute care patients.

Modified May 24, 2016 – MDH