Michael McMullan, MD

Michael McMullan, MD

Cardiac Surgery, Transplant Center, Hybrid Heart Procedures, Single Ventricle Program, Heart Failure Program, Cardiology, Fetal Care and Treatment Center, VAD Program

On staff since September 2007

Children's Title: Division Chief, Congenital Cardiac Surgery; Surgical Director, Cardiac Transplant; Director, Mechanical Cardiac Support and ECLS Services

Academic Title: Professor, Surgery

Research Center: Center for Integrative Brain Research

"I was drawn to pediatric cardiac surgery by the opportunity to make a very real difference in the lives of children with difficult medical problems. My greatest reward is helping these children live healthy, happy lives. We are privileged to have access to cutting-edge medical technology in this country. I work every day to apply this technology in ways that improve the quality of life for my patients."

  • Patient Testimonials

    • Emily Gig Harbor, WA 08.31.23

      8 years ago my son, Sam, was born with coarctation of the aorta and a huge VSD. Dr. McMullan gave me so much hope and even waited with us for our sons baptism before being wheeled away for emergency surgery. Our son is healthy and thriving… This mom heart could never thank him enough!

    • Stephanie Cascade, MT 06.30.23

      Dr McMullan was the best pediatric cardiology surgeon we could have possibly asked for! He was so kind and compassionate to us terrified parents. Several nurses commented after our son's surgery that his recovery seemed to be going so well because of Dr McMullan's incredible surgical skills. We pray our son won't need another surgery, but if he does we will definitely request Dr McMullan again!

    • Marc Sitka, AK 08.10.22

      My son is now 10.5 y/o, thanks to Dr. McMullan. He was born with TGA, had the arterial switch at 6 days old. He is very active and does plays sports. We can never thank you enough, you have that healing touch. The surgeons hand. All the RN’s and staff of Seattle Childrens Hospital, we thank you.

    Recommend Michael McMullan, MD

  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    Norman Shumway Award for Best Paper 37th Annual Meeting of the Western Thoracic Surgical Association (Senior Author) 2011
    Society of Thoracic Surgeons Clinical Research Training Scholarship 2004
    Award for Most Outstanding Scientific Paper International Symposium on Pediatric Cardiac Intensive Care, Miami 1996
    Sigma Alpha Mu Samuel Miller Award for Scientific Research Award 1993
    Sarnoff Cardiovascular Research Foundation Research Award 1992
    Aaron Hartman Award for Outstanding Student in Psychology Tulane University 1989

  • Publications

    Manuscripts in Refereed Journals

    • Smith KM, McMullan DM, Bratton SL, Rycus P, Kinsella JP, Brogan TV
      Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
      24603452 Journal of perinatology : official journal of the California Perinatal Association, 2014 May : 34(5)386-91
    • Hong BJ, Delaney M, Guynes A, Warner P, McMullan DM, Kemna MS, Boucek RJ, Law YM
      Human leukocyte antigen sensitization in pediatric patients exposed to mechanical circulatory support.
      24469294 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2014 May : 60(3)317-21
    • Mesher AL, McMullan DM
      Extracorporeal life support for the neonatal cardiac patient: outcomes and new directions.
      24580765 Seminars in perinatology, 2014 March : 38(2)97-103
    • Karamlou T, Welke KF, McMullan DM, Cohen GA, Gelow J, Tibayan FA, Mudd JM, Slater MS, Song HK
      Combined heart-kidney transplant improves post-transplant survival compared with isolated heart transplant in recipients with reduced glomerular filtration rate: Analysis of 593 combined heart-kidney transplants from the United Network Organ Sharing Database.
      24183335 The Journal of thoracic and cardiovascular surgery, 2014 Jan. : 147(1)456-461.e1
    • McMullan DM, Thiagarajan RR, Smith KM, Rycus PT, Brogan TV
      Extracorporeal cardiopulmonary resuscitation outcomes in term and premature neonates*.
      24141660 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014 Jan. : 15(1)e9-e16
    • Symons JM, McMahon MW, Karamlou T, Parrish AR, McMullan DM
      Continuous renal replacement therapy with an automated monitor is superior to a free-flow system during extracorporeal life support.
      23965637 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 Nov. : 14(9)e404-8
    • MacIver RH, Permut LC, McMullan DM
      Downsized Contegra graft as a right ventricle-to-pulmonary artery conduit in the setting of mediastinitis.
      23992706 The Annals of thoracic surgery, 2013 Sept. : 96(3)1077-8
    • Delaney M, Axdorff-Dickey RL, Crockett GI, Falconer AL, Levario MJ, McMullan DM
      Risk of extracorporeal life support circuit-related hyperkalemia is reduced by prebypass ultrafiltration.
      23823207 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 July : 14(6)e263-7
    • Lequier L, Horton SB, McMullan DM, Bartlett RH
      Extracorporeal membrane oxygenation circuitry.
      23735989 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 June : 14(5 Suppl 1)S7-12
    • MacLaren G, Dodge-Khatami A, Dalton HJ, Writing Committee, MacLaren G, Dodge-Khatami A, Dalton HJ, Adachi I, Almodovar M, Annich G, Bartlett R, Bronicki R, Brown K, Butt W, Cooper D, Demuth M, D'Udekem Y, Fraser C, Guerguerian AM, Heard M, Horton S, Ichord R, Jaquiss R, Laussen P, Lequier L, Lou S, Marino B, McMullan M, Ogino M, Peek G, Pretre R, Rodefeld M, Schmidt A, Schwartz S, Shekerdemian L, Shime N, Sivarajan B, Stiller B, Thiagarajan R
      Joint statement on mechanical circulatory support in children: a consensus review from the Pediatric Cardiac Intensive Care Society and Extracorporeal Life Support Organization.
      23735979 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 June : 14(5 Suppl 1)S1-2
    • Doorenbos AZ, Starks H, Bourget E, McMullan DM, Lewis-Newby M, Rue TC, Lindhorst T, Aisenberg E, Oman N, Curtis JR, Hays R, Seattle Ethics in ECLS (SEE) Consortium, Clark JD, Baden HP, Brogan TV, Di Gennaro JL, Mazor R, Roberts JS, Turnbull J, Wilfond BS
      Examining palliative care team involvement in automatic consultations for children on extracorporeal life support in the pediatric intensive care unit.
      23540309 Journal of palliative medicine, 2013 May : 16(5)492-5 PMCID:PMC3705963
    • McMullan DM
      Expanding the availability of extracorporeal cardiopulmonary resuscitation.
      23382440 Pediatrics, 2013 March : 131(3)e934-8
    • Karamlou T, Vafaeezadeh M, Parrish AM, Cohen GA, Welke KF, Permut L, McMullan DM
      Increased extracorporeal membrane oxygenation center case volume is associated with improved extracorporeal membrane oxygenation survival among pediatric patients.
      23246046 The Journal of thoracic and cardiovascular surgery, 2013 Feb. : 145(2)470-5
    • Subramanian S, Vafaeezadeh M, Parrish AR, McMullan DM
      Comparison of wire-reinforced and non-wire-reinforced dual-lumen catheters for venovenous ECMO in neonates and infants.
      23263340 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2013 Jan. : 59(1)81-5
    • McMullan DM
      Should intravenous immunoglobulin be given to patients with postoperative chylothorax?.
      22955461 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2012 Sept. : 13(5)599-600
    • McMullan DM
      Clinical management of pediatric tracheo-bronchomalacia.
      21897163 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2011 Sept. : 12(5)599-600
    • Salerno JC, Seslar SP, Chun TU, Vafaeezadeh M, Parrish AR, Permut LC, Cohen GA, McMullan DM
      Predictors of ECMO support in infants with tachycardia-induced cardiomyopathy.
      21448617 Pediatric cardiology, 2011 Aug. : 32(6)754-8
    • Hermes HM, Cohen GA, Mehrotra AK, McMullan DM, Permut LC, Goodwin S, Stevens AM
      Association of thymectomy with infection following congenital heart surgery.
      23803985 World journal for pediatric and congenital heart surgery, 2011 July : 2(3)351-8
    • McMullan DM, Emmert JA, Permut LC, Mazor RL, Jeffries HE, Parrish AR, Baden HP, Cohen GA
      Minimizing bleeding associated with mechanical circulatory support following pediatric heart surgery.
      20801051 European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011 March : 39(3)392-7
    • Subramanian S, Clark JD, Jeffries HE, McMullan DM
      Novel pH1N1 viral cardiomyopathy requiring veno-venous extracorporeal membrane oxygenation.
      20453697 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2010 Nov. : 11(6)714-7
    • McMullan DM
      Relative risks of recombinant factor VII.
      19741450 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2009 Sept. : 10(5)604-5
    • McMullan DM, Reddy VM, Gottliebson WM, Silverman NH, Perry SB, Chan F, Hanley FL, Riemer RK
      Morphological studies of pulmonary arteriovenous shunting in a lamb model of superior cavopulmonary anastomosis.
      18043856 Pediatric cardiology, 2008 July : 29(4)706-12 PMCID:PMC2970565
    • Oppido G, Davies B, McMullan DM, Cochrane AD, Cheung MM, d'Udekem Y, Brizard CP
      Surgical treatment of congenital mitral valve disease: midterm results of a repair-oriented policy.
      18544378 The Journal of thoracic and cardiovascular surgery, 2008 June : 135(6)1313-20; discussion 1320-1
    • McMullan DM, Oppido G, Davies B, Kawahira Y, Cochrane AD, d'Udekem d'Acoz Y, Penny DJ, Brizard CP
      Surgical strategy for the bicuspid aortic valve: tricuspidization with cusp extension versus pulmonary autograft.
      17599491 The Journal of thoracic and cardiovascular surgery, 2007 July : 134(1)90-8
    • McMullan DM, Moulick A, Jonas RA
      Late embolization of Amplatzer patent ductus arteriosus occlusion device with thoracic aorta embedment.
      17307488 The Annals of thoracic surgery, 2007 March : 83(3)1177-9
    • McMullan DM, Dalton HJ
      Extracorporeal support in hypoplastic left heart syndrome: who and why?
      16829830 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006 July : 7(4)390-1
    • McMullan DM, Oppido G, Alphonso N, Cochrane AD, d'Acoz Yd, Brizard CP
      Evaluation of downsized homograft conduits for right ventricle-to-pulmonary artery reconstruction.
      16798304 The Journal of thoracic and cardiovascular surgery, 2006 July : 132(1)66-71
    • Parry AJ, McMullan DM, Yelich S, Hanley FL
      Profile of serum S100beta levels during maturation in fetal and neonatal sheep.
      16586228 American journal of perinatology, 2006 April : 23(3)153-8
    • McMullan DM, McBride M, Livesay JJ, Dougherty KG, Krajcer Z
      Celiac artery aneurysm: a case report.
      16878636 Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital, 2006 : 33(2)235-40 PMCID:PMC1524716
    • McMullan DM
      Overview of the Thoracic Surgery Residents Association
      Annals of Thoracic Surgery, 2006 : 81(3)1180
    • McMullan DM, Cohen GA
      Images in clinical medicine. Radiographic evidence linking tobacco use and lung cancer.
      16436771 The New England journal of medicine, 2006 Jan. : 354(4)397
    • DeLaRosa J, Thourani VH, Wheatley GH 3rd, McMullan DM, Karamanoukian RL, Greene MG, Morales DL
      Impact of resident duty hour standards on cardiothoracic residents and program directors.
      16242419 The Annals of thoracic surgery, 2005 Nov. : 80(5)1569-71
    • McMullan DM, Hanley FL, Cohen GA, Portman MA, Riemer RK
      Pulmonary arteriovenous shunting in the normal fetal lung.
      15464334 Journal of the American College of Cardiology, 2004 Oct. : 44(7)1497-500
    • McMullan DM, Hanley FL, Riemer RK
      A method for selectively limiting lumen diameter in corrosion casting.
      15121445 Microvascular research, 2004 May : 67(3)215-7
    • Gaissert HA, Casale AS, Creswell LL, Ferguson TB Jr, Fullerton DA, Kernstine KH, McMullan DM, Ring WS, Putnam JB Jr, Society of Thoracic Surgeons Workforce on Clinical Trials
      Mentoring clinical trials in thoracic and cardiovascular surgery: a new role for the Society of Thoracic Surgeons.
      15111218 The Annals of thoracic surgery, 2004 May : 77(5)1874-5
    • McMullan DM, Wood DE
      Pulmonary carcinoid tumors.
      12973707 Seminars in thoracic and cardiovascular surgery, 2003 July : 15(3)289-300
    • McMullan DM, Wilansky S, Frazier OH
      Ventricular fibrillation in a heterotopic heart transplant recipient.
      12607690 The Annals of thoracic surgery, 2003 Feb. : 75(2)598
    • Malhotra SP, Reddy VM, Thelitz S, He YP, McMullan DM, Hanley FL, Riemer RK
      The role of oxidative stress in the development of pulmonary arteriovenous malformations after cavopulmonary anastomosis.
      12202863 The Journal of thoracic and cardiovascular surgery, 2002 Sept. : 124(3)479-85
    • Black SM, Bekker JM, McMullan DM, Parry AJ, Ovadia B, Reinhartz O, Lakshminrushimha S, Mata-Greenwood E, Steinhorn RH, Fineman JR
      Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow.
      12149501 Pediatric research, 2002 Aug. : 52(2)233-44
    • McMullan DM, Patel V, Radovancevic B, Hochman FL, Frazier OH
      Cytomegalovirus cholecystitis in a heart transplant recipient.
      12072337 Transplantation proceedings, 2002 June : 34(4)1271-2
    • Gutierrez JA, Parry AJ, McMullan DM, Chapin CJ, Fineman JR
      Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow.
      11597919 American journal of physiology. Lung cellular and molecular physiology, 2001 Nov. : 281(5)L1264-70
    • Wedgwood S, McMullan DM, Bekker JM, Fineman JR, Black SM
      Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
      11509453 Circulation research, 2001 Aug. : 89(4)357-64
    • McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR
      Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1.
      11158977 American journal of physiology. Heart and circulatory physiology, 2001 Feb. : 280(2)H777-85
    • McMullan DM, Radovaneevi B, Jackow CM, Frazier OH, Duvic M
      Cutaneous T-cell lymphoma in a cardiac transplant recipient.
      11678256 Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital, 2001 : 28(3)203-7 PMCID:PMC101179
    • McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Kon A, Heidersbach RS, Black SM, Fineman JR
      Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow.
      11082382 Circulation, 2000 Nov. : 102(19 Suppl 3)III172-8
    • Beyer EA, McMullan DM, Delgado R, Gregoric I, Radovancevic B, Frazier OH
      Normalization of native heart function years after heterotopic transplantation.
      11093512 The Annals of thoracic surgery, 2000 Nov. : 70(5)1690-1; discussion 1691-2
    • McMullan DM, Beyer EA, Gregoric I, Radovancevic B, Frazier OH
      Left ventricular reduction in a Jehovah's Witness.
      11016342 The Annals of thoracic surgery, 2000 Sept. : 70(3)958-60; discussion 960-1
    • Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR
      Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension.
      10564139 The American journal of physiology, 1999 Nov. : 277(5 Pt 2)H1849-56
    • Petrossian E, Parry AJ, Reddy VM, Akkersdijk GP, McMullan DM, Thompson L, Hendricks-Munoz KD, Hallak H, Hanley FL, Fineman JR
      Endothelin receptor blockade prevents the rise in pulmonary vascular resistance after cardiopulmonary bypass in lambs with increased pulmonary blood flow.
      9918974 The Journal of thoracic and cardiovascular surgery, 1999 Feb. : 117(2)314-23
    • Panis Y, McMullan DM, Emond JC
      Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection.
      9037225 Surgery, 1997 Feb. : 121(2)142-9
    • Lyson T, McMullan DM, Ermel LD, Morgan BJ, Victor RG
      Mechanism of cyclosporine-induced sympathetic activation and acute hypertension in rats.
      8175178 Hypertension, 1994 May : 23(5)667-75
    • Dohanich GP, McMullan DM, Cada DA, Mangum KA
      Muscarinic receptor subtypes and sexual behavior in female rats.
      1708147 Pharmacology, biochemistry, and behavior, 1991 Jan. : 38(1)115-24
    • Dohanich GP, McMullan DM, Brazier MM
      Cholinergic regulation of sexual behavior in female hamsters.
      2326327 Physiology and behavior, 1990 Jan. : 47(1)127-31

    Published Books, Videos, Software, etc.

    • Tran H, Le TP, McMullan, DM, Wilkinson JL (eds)
      Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries
      Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City, 2008

    Published Abstracts

    • Dohanich GP, Holland R, McMullan DM and Piazza A, Cada DA
      Inhibition of lordosis in rats and hamsters by muscarinic antagonists
      Society for Neuroscience Abstracts, 1988 : 14(1)275
    • Parry AJ, McMullan DM, Yelich S, Riemer RK, Hanley FL
      The impact of fetal exposure on hemodynamics, white cell activation, and the stress response
      Pediatric Research, 2001 : 49(4 Part 2)56a, I1
    • Panis Y, Hayes-Lattin B, McMullan DM, Ascher NL, Emond JC
      Arginase serum profile after extensive hepatectomy in rats
      Hepatology, 1993 : 18(4 Part 2)192A
    • Nishimura N, Radovancevic B, Odegaard P, Meyers TJ, Springer WE, Beyer EAK, McMullan DM, Frazier OH
      Patients with renal dysfunction before left ventricular assist system (LVAS) implantation are poor transplant candidates and permanent LVAS may be indicated
      Journal of Heart and Lung Transplantation, 1997 : 16(1)94
    • Michael McMullan, MD, McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR
      Inhaled nitric oxide-induced rebound pulmonary hypertension: a role for endothelin-1
      American Physiology Society, 2000 : 70577H
    • McMullan DM, He Y, Hanley FL, Reddy VM, Riemer RK
      Abnormal pulmonary vascular response to cavopulmonary anastomosis: increased angiogenic signaling
      Circulation, 1999 : 100(18)I170
    • McMullan DM, Bekker JM, Johengen MJ, Heidersbach RS, Black SK, Fineman JR
      Rebound pulmonary hypertension following inhaled nitric oxide therapy: a role for endothelin-1
      Journal of Thoracic and Cardiovascular Surgery, 2000 : 119(3)651
    • Riemer RK, McMullan DM, Malhotra SP, He YP, Reddy VM
      Upregulation of Tie-2 but not Tie-1 expression in a model of pulmonary arteriovenous malformations induced by alteration of pulmonary blood flow
      FASEB Journal, 2000 : 14(4)A686
    • Linam J, Permut LC, McMullan DM, Morscheck AR, Cohen GA
      The Konno procedure for left ventricular outflow tract obstruction in pediatric patients
      Journal of Investigative Medicine, 2009 : 57(1)481
    • Baileselassie B, Allen J, Soriano B, Bhat A, Boucek R, Kemna M, Law S, Albers E, McMullan DM, Lay Y
      Correlation of B-type natriuretic peptide (BNP) with echocardiographic and catheterization parameters in pediatric heart recipients
      Journal of Heart and Lung Transplantation, 2013 : 32(4S)S241
    • Lyson T, McMullan DM, Ermel LD, Morgan BJ, Victor RG
      Neural mechanisms of cyclosporine induced hypertension
      Clinical Research, 1990 : 38(4)947A
    • Mesher AL, Brogan TV, Kim K, Chen JM, McMullan DM
      Prematurity negatively impacts cardiac extracorporeal life support survival
      Journal of Surgical Research, 2014 : 186(2)600
    • Law S, Brogan TV, Law Y, McMullan DM
      Age and era-based survival differences in thoracic transplantation patients who require ECMO
      Journal of Heart and Lung Transplantation, 2013 : 32(4S)S25
    • McMullan DM, Bumgardner GL, Hayes-Lattin B, Osorio RW, Ascher NL
      Arginase as an indicator of acute vs. ongoing hepatocellular damage
      Hepatology, 1993 : 18(4 Part 2)338a
    • Baumgardner GL, McMullan DM, Lin Z, Konstantinides FN, Cerra FB, Fasola C, Ascher NL
      The role of arginase in liver immunity
      Hepatology, 1993 : 18(4 Part 2)211a
    • Alphonso N, Taib R, Guerrero R, McMullan DM, d'Udekem d'Acoz YAC, Penny D, Brizard CP
      Elective rapid re-training of the deconditioned left ventricle after the arterial switch operation with a left ventricular assist device
      Journal of Thoracic and Cardiovascular Surgery, 2005 : 129(3)715
    • Riemer RK, McMullan DM, He Y, Hanley FL, Reddy VM
      Altered pulmonary gene expression following cavopulmonary anastomosis in young lambs
      Circulation, 1998 : 98(17)1268-9
    • Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR
      A potential mechanism for rebound pulmonary hypertension
      Critical Care Medicine, 1999 : 27A39
    • Gutierrez JA, Parry AJ, McMullan DM, Fineman JR
      Increased pulmonary blood flow decreases protein A in a lamb model of congenital heart disease
      352A Pediatric Research, 1999 : Pediatric(45)4
    • McMullan DM, Riemer RK, Gottliebson WM, Kung GC, Yelich S, Reddy VM, Hanley FL
      Pulmonary arteriovenous shunting in fetal and neonatal lambs
      Pediatric Research, 1999 : 45(4 Part 2)27a, I1
    • McMullan DM, Riemer RK, Gottliebson WM, Kung GC, Petrossian E, Hanley FL
      Pulmonary arteriovenous connections in fetal lambs
      Pediatric Research, 1999 : 45(4)27A
    • Riemer RK, McMullan DM, He Y, Hanley FL, Reddy VM
      Increased ecNOS expression after cavopulmonary anastomosis
      Federation of American Societies for Experimental Biology Journal, 1999 : 13(4 Part 1)A103
    • DeLaRosa J, Thourani VH, Wheatley GH, McMullan DM, Karamanoukian RL, Morales DL
      The impact of resident duty hour standards: a survey of cardiothoracic surgery residents and program directors
      Annals of Thoracic Surgery, 2004 : 78(6)2227
    • McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Heidersbach RS, Kon AA, Black SK, Fineman JR
      Endogenous nitric oxide production after cardiopulmonary bypass (CPB) in lambs with normal and increased pulmonary blood flow
      Circulation, 1999 : 100(18)I70
    • Michael McMullan, MD, Thelitz S, McMullan DM, Ovadia B, Bekker JM, Johengen MJ, Black SM, Sanchez LS, Fineman JR
      Inhaled nitric oxide alters endogenous phosphodiesterase activity in lambs
      Circulation, 2000 : 102(8)II-320
    • Michael McMullan, MD, Malhotra SP, Reinhartz O, McMullan DM, Thelitz S, Bekker JM, Johengen MJ, Ovadia B, He YP, Riemer RK, Fineman JR
      Alterations in the angiotensin system induced by increased pulmonary blood flow in lambs with pulmonary hypertension
      Critical Care Medicine, 2000 : 28A70
    • Parry AJ, McMullan DM, Bekker JM, Johengen MJ, Heidersbach RS, Kon AA, Black SK, Fineman JR
      Endogenous nitric oxide production in a model of congenital heart disease with increased pulmonary blood flow: an 8 week follow-up
      Circulation, 1999 : 100(18)I-735
    • Wedgwood S, McMullan DM, Bekker JM, Fineman, Black SM
      ETA receptor blockade preserves NOS activity during inhaled NO therapy: a role for ET-1-induced superoxide production
      Circulation, 2000 : 102(18)II-169
    • McMullan DM, Bumgardner GL, Hayes-Lattin B, Osorio RW, Ascher NL
      Preoperative serum arginase level as a predictor of rejection in human orthotopic liver recipients
      Hepatology, 1993 : 18(4 Part 2)338a
    • Ideen C, Albers E, Law Y, Warner P, McMullan DM, Permut L, Kemna M
      Effect of initial surgical palliation on HLA sensitization and outcomes in children transplanted for hypoplastic left heart syndrome (HLHS)
      Journal of Heart and Lung Transplantation, 2013 : 32(4S)S652
    • Gottliebson WM, Cai L, McMullan DM, Brook MM, Schiller NB, Glantz SA
      Cardiac chamber interaction and the pericardium
      Circulation, 2001 : 104(17)II-564

    Other Publications

    • Conrad SA, Broman LM, Taccone FS, Lorusso R, Malfertheiner MV, Pappalardo F, Di Nardo M, Belliato M, Grazioli L, Barbaro RP, McMullan DM, Pellegrino V, Brodie D, Bembea MM, Fan E, Mendonca M, Diaz R, Bartlett RH
      The Extracorporeal Life Support Organization Maastricht Treaty for Nomenclature in Extracorporeal Life Support. A Position Paper of the Extracorporeal Life Support Organization.
      29614239 American journal of respiratory and critical care medicine, 2018 Apr 3
    • Capatos G, Burke CR, Ogino MT, Lorusso RR, Brogan TV, McMullan DM, Dalton HJ
      Venovenous extracorporeal life support in patients with HIV infection and Pneumocystis jirovecii pneumonia.
      29528776 Perfusion, 2018 Mar 1 : 267659118765595
    • Law SP, Oron AP, Kemna MS, Albers EL, McMullan DM, Chen JM, Law YM
      Comparison of Transplant Waitlist Outcomes for Pediatric Candidates Supported by Ventricular Assist Devices Versus Medical Therapy.
      29438111 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018 Feb 12
    • Turek JW, Nellis JR, Sherwood BG, Kotagal M, Mesher AL, Thiagarajan RR, Patel SS, Avansino JR, Rycus PT, McMullan DM, Brogan TV
      Shifting Risks and Conflicting Outcomes-ECMO for Neonates with Congenital Diaphragmatic Hernia in the Modern Era.
      29144241 The Journal of pediatrics, 2017 Nov. : 190163-168.e4
    • Bermudez CA, McMullan DM
      Extracorporeal life support in preoperative and postoperative heart transplant management.
      29152498 Annals of translational medicine, 2017 Oct. : 5(20)398 PMCID:PMC5673791
    • Burke CR, Chan T, McMullan DM
      Extracorporeal Life Support Use in Adult Burn Patients.
      27606550 Journal of burn care and research : official publication of the American Burn Association, 2017 May : 38(3)174-178
    • Burke CR, Chan T, Brogan TV, McMullan DM
      Pediatric extracorporeal cardiopulmonary resuscitation during nights and weekends.
      28263789 Resuscitation, 2017 May : 11447-52
    • Chan T, Di Gennaro J, Farris RW, Radman M, McMullan DM
      Racial and Ethnic Variation in Pediatric Cardiac Extracorporeal Life Support Survival.
      28291093 Critical care medicine, 2017 April : 45(4)670-678
    • Burke CR, Chan T, Rubio AE, McMullan DM
      Early Cardiac Catheterization Leads to Shortened Pediatric Extracorporeal Membrane Oxygenation Run Duration.
      28271557 Journal of interventional cardiology, 2017 April : 30(2)170-176
    • Yam N, McMullan DM
      Extracorporeal cardiopulmonary resuscitation.
      28275617 Annals of translational medicine, 2017 Feb. : 5(4)72 PMCID:PMC5337222
    • Thiagarajan RR, Barbaro RP, Rycus PT, Mcmullan DM, Conrad SA, Fortenberry JD, Paden ML, ELSO member centers.
      Extracorporeal Life Support Organization Registry International Report 2016.
      27984321 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2017 Jan. : 63(1)60-67
    • Burke CR, Crown A, Chan T, McMullan DM
      Extracorporeal life support is safe in trauma patients.
      27866648 Injury, 2017 Jan. : 48(1)121-126
    • Geisser DL, McMullan DM, Jones TK, Kemna MS, Law YM
      Application of the hybrid Stage 1 palliation concept to patients without hypoplastic left heart syndrome as a bridge to heart transplant.
      27425401 The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2016 Sept. : 35(9)1133-5
    • Ford MA, Gauvreau K, McMullan DM, Almodovar MC, Cooper DS, Rycus PT, Thiagarajan R
      Factors Associated With Mortality in Neonates Requiring Extracorporeal Membrane Oxygenation for Cardiac Indications: Analysis of the Extracorporeal Life Support Organization Registry Data.
      27355824 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016 Sept. : 17(9)860-70
    • Burke CR, Chan T, Brogan TV, Lequier L, Thiagarajan RR, Rycus PT, McMullan DM
      Extracorporeal life support for victims of drowning.
      27107689 Resuscitation, 2016 July : 10419-23
    • Eilers B, Albers E, Law Y, McMullan DM, Shaw D, Kemna M
      Posterior reversible encephalopathy syndrome after pediatric heart transplantation: Increased risk for children with preexisting Glenn/Fontan physiology.
      27139146 Pediatric transplantation, 2016 June : 20(4)552-8
    • Latham GJ, Jefferis Kirk C, Falconer A, Dickey R, Albers EL, McMullan DM
      Challenging Argatroban Management of a Child on Extracorporeal Support and Subsequent Heart Transplant.
      26721808 Seminars in cardiothoracic and vascular anesthesia, 2016 June : 20(2)168-74
    • McMullan DM
      Is There a Concerning Trend in Extracorporeal Life Support Utilization for Single-Ventricle Patients?
      26945198 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2016 March : 17(3)259-60
    • Kemna M, Albers E, Bradford MC, Law S, Permut L, McMullan DM, Law Y
      Impact of donor-recipient sex match on long-term survival after heart transplantation in children: An analysis of 5797 pediatric heart transplants.
      26690968 Pediatric transplantation, 2016 March : 20(2)249-55
    • Burke CR, McMullan DM
      Extracorporeal Life Support for Pediatric Heart Failure.
      27812522 Frontiers in pediatrics, 2016 : 4115 PMCID:PMC5071357
    • Likes ML, Silverman NH, Albers EL, Choy R, Bhat A, McMullan DM
      Near-fatal neonatal coronary ischaemia associated with intermittent aortic regurgitation: successful surgical treatment.
      26675600 Cardiology in the young, 2015 Dec. : 25(8)1531-5
    • Chasovskyi K, Fedevych O, McMullan DM, Mykychak Y, Vorobiova G, Zhovnir V, Yemets I
      Tissue perfusion in neonates undergoing open-heart surgery using autologous umbilical cord blood or donor blood components.
      25249520 Perfusion, 2015 Sept. : 30(6)499-506
    • Wong TE, Delaney M, Gernsheimer T, Matthews DC, Brogan TV, Mazor R, McMullan DM, Reiner AP, Konkle BA
      Antithrombin concentrates use in children on extracorporeal membrane oxygenation: a retrospective cohort study.
      25581634 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2015 March : 16(3)264-9
    • Weldin JD, Kapur RP, Lewin MB, McMullan DM
      Fatal spontaneous dissection of a Contegra conduit in a child.
      25742831 The Annals of thoracic surgery, 2015 March : 99(3)1062-4
    • McMullan DM, Riemer RK
      Embryology and anatomy of intrapulmonary shunts.
      25693623 Echocardiography (Mount Kisco, N.Y.), 2015 Feb. : 32 Suppl 3S190-4
    • Mesher AL, Hermsen JL, Rubio AE, Chen JM, McMullan DM
      Neoaortic thrombus after Norwood procedure: complication of extracorporeal life support?
      25639418 The Annals of thoracic surgery, 2015 Feb. : 99(2)709-10
    • Witt CE, Mesher AL, Hermsen JL, Brogan TV, McMullan DM
      Intrapleural fibrinolysis during pediatric extracorporeal life support.
      25548359 World journal for pediatric and congenital heart surgery, 2015 Jan. : 6(1)123-5
    • Guynes A, Delaney M, McMullan DM, Townsend-McCall D, Kemna M, Boucek R, Law YM
      ABO blood group antibody levels in infants exposed to mechanical circulatory support.
      25158885 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2014 Nov. : 60(6)737-9
    • Hermsen JL, Permut LC, McQuinn TC, Jones TK, Chen JM, McMullan DM
      Tricuspid valve replacement with a melody stented bovine jugular vein conduit.
      25441796 The Annals of thoracic surgery, 2014 Nov. : 98(5)1826-7
    • Karamlou T, Jacobs ML, Pasquali S, He X, Hill K, O'Brien S, McMullan DM, Jacobs JP
      Surgeon and center volume influence on outcomes after arterial switch operation: analysis of the STS Congenital Heart Surgery Database.
      25069686 The Annals of thoracic surgery, 2014 Sept. : 98(3)904-11
    • Adler AL, Smith J, Permut LC, McMullan DM, Zerr DM
      Significance of positive mediastinal cultures in pediatric cardiovascular surgical procedure patients undergoing delayed sternal closure.
      24881862 The Annals of thoracic surgery, 2014 Aug. : 98(2)685-90
    • McMullan DM
      How does one use extracorporeal cardiopulmonary resuscitation risk factor data?
      25000422 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014 July : 15(6)567-8
    • Karamlou T, Sexson K, Parrish A, Welke KF, McMullan DM, Permut L, Cohen G
      One size does not fit all: the influence of age at surgery on outcomes following Norwood operation.
      24928488 Journal of cardiothoracic surgery, 2014 Jun 14 : 9100 PMCID:PMC4080783
    • Smith KM, McMullan DM, Bratton SL, Rycus P, Kinsella JP, Brogan TV
      Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
      24603452 Journal of perinatology : official journal of the California Perinatal Association, 2014 May : 34(5)386-91
    • Hong BJ, Delaney M, Guynes A, Warner P, McMullan DM, Kemna MS, Boucek RJ, Law YM
      Human leukocyte antigen sensitization in pediatric patients exposed to mechanical circulatory support.
      24469294 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2014 May : 60(3)317-21
    • Mesher AL, McMullan DM
      Extracorporeal life support for the neonatal cardiac patient: outcomes and new directions.
      24580765 Seminars in perinatology, 2014 March : 38(2)97-103
    • McMullan DM, Permut LC, Jones TK, Johnston TA, Rubio AE
      Modified Blalock-Taussig shunt versus ductal stenting for palliation of cardiac lesions with inadequate pulmonary blood flow.
      24071469 The Journal of thoracic and cardiovascular surgery, 2014 Jan. : 147(1)397-401
    • McMullan DM, Thiagarajan RR, Smith KM, Rycus PT, Brogan TV
      Extracorporeal cardiopulmonary resuscitation outcomes in term and premature neonates*.
      24141660 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2014 Jan. : 15(1)e9-e16
    • Karamlou T, Welke KF, McMullan DM, Cohen GA, Gelow J, Tibayan FA, Mudd JM, Slater MS, Song HK
      Combined heart-kidney transplant improves post-transplant survival compared with isolated heart transplant in recipients with reduced glomerular filtration rate: Analysis of 593 combined heart-kidney transplants from the United Network Organ Sharing Database.
      24183335 The Journal of thoracic and cardiovascular surgery, 2014 Jan. : 147(1)456-461.e1
    • Hillman SC, Barton PM, Roberts TE, Maher ER, McMullan DM, Kilby MD
      BAC chromosomal microarray for prenatal detection of chromosome anomalies in fetal ultrasound anomalies: an economic evaluation.
      24943865 Fetal diagnosis and therapy, 2014 : 36(1)49-58
    • Symons JM, McMahon MW, Karamlou T, Parrish AR, McMullan DM
      Continuous renal replacement therapy with an automated monitor is superior to a free-flow system during extracorporeal life support.
      23965637 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 Nov. : 14(9)e404-8
    • MacIver RH, Permut LC, McMullan DM
      Downsized Contegra graft as a right ventricle-to-pulmonary artery conduit in the setting of mediastinitis.
      23992706 The Annals of thoracic surgery, 2013 Sept. : 96(3)1077-8
    • Delaney M, Axdorff-Dickey RL, Crockett GI, Falconer AL, Levario MJ, McMullan DM
      Risk of extracorporeal life support circuit-related hyperkalemia is reduced by prebypass ultrafiltration.
      23823207 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 July : 14(6)e263-7
    • Lequier L, Horton SB, McMullan DM, Bartlett RH
      Extracorporeal membrane oxygenation circuitry.
      23735989 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2013 June : 14(5 Suppl 1)S7-12 PMCID:PMC3742331
    • Doorenbos AZ, Starks H, Bourget E, McMullan DM, Lewis-Newby M, Rue TC, Lindhorst T, Aisenberg E, Oman N, Curtis JR, Hays R, Seattle Ethics in ECLS (SEE) Consortium., Clark JD, Baden HP, Brogan TV, Di Gennaro JL, Mazor R, Roberts JS, Turnbull J, Wilfond BS
      Examining palliative care team involvement in automatic consultations for children on extracorporeal life support in the pediatric intensive care unit.
      23540309 Journal of palliative medicine, 2013 May : 16(5)492-5 PMCID:PMC3705963
    • McMullan DM
      Expanding the availability of extracorporeal cardiopulmonary resuscitation.
      23382440 Pediatrics, 2013 March : 131(3)e934-8
    • Karamlou T, Vafaeezadeh M, Parrish AM, Cohen GA, Welke KF, Permut L, McMullan DM
      Increased extracorporeal membrane oxygenation center case volume is associated with improved extracorporeal membrane oxygenation survival among pediatric patients.
      23246046 The Journal of thoracic and cardiovascular surgery, 2013 Feb. : 145(2)470-5
    • Subramanian S, Vafaeezadeh M, Parrish AR, McMullan DM
      Comparison of wire-reinforced and non-wire-reinforced dual-lumen catheters for venovenous ECMO in neonates and infants.
      23263340 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2013 Jan. : 59(1)81-5
    • Permut LC, McMullan DM, Soriano BD
      Long-term mechanical cardiac assist in children: a work in progress.
      23261368 Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2013 Jan. : 26(1)50-1
    • McMullan DM
      Should intravenous immunoglobulin be given to patients with postoperative chylothorax?.
      22955461 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2012 Sept. : 13(5)599-600
    • McMullan DM
      Clinical management of pediatric tracheo-bronchomalacia.
      21897163 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2011 Sept. : 12(5)599-600
    • Salerno JC, Seslar SP, Chun TU, Vafaeezadeh M, Parrish AR, Permut LC, Cohen GA, McMullan DM
      Predictors of ECMO support in infants with tachycardia-induced cardiomyopathy.
      21448617 Pediatric cardiology, 2011 Aug. : 32(6)754-8
    • Hermes HM, Cohen GA, Mehrotra AK, McMullan DM, Permut LC, Goodwin S, Stevens AM
      Association of thymectomy with infection following congenital heart surgery.
      23803985 World journal for pediatric and congenital heart surgery, 2011 Jul 1 : 2(3)351-8
    • Cohen GA, Permut LC, Arakaki LS, Ciesielski WA, McMullan DM, Parrish AR, Schenkman KA
      Direct optical measurement of intraoperative myocardial oxygenation during congenital heart surgery.
      21508828 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2011 July : 57(4)314-7
    • McMullan DM, Emmert JA, Permut LC, Mazor RL, Jeffries HE, Parrish AR, Baden HP, Cohen GA
      Minimizing bleeding associated with mechanical circulatory support following pediatric heart surgery.
      20801051 European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2011 March : 39(3)392-7
    • Subramanian S, Clark JD, Jeffries HE, McMullan DM
      Novel pH1N1 viral cardiomyopathy requiring veno-venous extracorporeal membrane oxygenation.
      20453697 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2010 Nov. : 11(6)714-7
    • McMullan DM
      Relative risks of recombinant factor VII.
      19741450 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2009 Sept. : 10(5)604-5
    • McMullan DM, Reddy VM, Gottliebson WM, Silverman NH, Perry SB, Chan F, Hanley FL, Riemer RK
      Morphological studies of pulmonary arteriovenous shunting in a lamb model of superior cavopulmonary anastomosis.
      18043856 Pediatric cardiology, 2008 July : 29(4)706-12 PMCID:PMC2970565
    • Oppido G, Davies B, McMullan DM, Cochrane AD, Cheung MM, d'Udekem Y, Brizard CP
      Surgical treatment of congenital mitral valve disease: midterm results of a repair-oriented policy.
      18544378 The Journal of thoracic and cardiovascular surgery, 2008 June : 135(6)1313-20; discussion 1320-1
    • McMullan DM, Oppido G, Davies B, Kawahira Y, Cochrane AD, d'Udekem d'Acoz Y, Penny DJ, Brizard CP
      Surgical strategy for the bicuspid aortic valve: tricuspidization with cusp extension versus pulmonary autograft.
      17599491 The Journal of thoracic and cardiovascular surgery, 2007 July : 134(1)90-8
    • McMullan DM, Moulick A, Jonas RA
      Late embolization of Amplatzer patent ductus arteriosus occlusion device with thoracic aorta embedment.
      17307488 The Annals of thoracic surgery, 2007 March : 83(3)1177-9
    • McMullan DM, Dalton HJ
      Extracorporeal support in hypoplastic left heart syndrome: who and why?
      16829830 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006 July : 7(4)390-1
    • McMullan DM, Oppido G, Alphonso N, Cochrane AD, d'Acoz Yd, Brizard CP
      Evaluation of downsized homograft conduits for right ventricle-to-pulmonary artery reconstruction.
      16798304 The Journal of thoracic and cardiovascular surgery, 2006 July : 132(1)66-71
    • Parry AJ, McMullan DM, Yelich S, Hanley FL
      Profile of serum S100beta levels during maturation in fetal and neonatal sheep.
      16586228 American journal of perinatology, 2006 April : 23(3)153-8
    • McMullan DM, Cohen GA
      Images in clinical medicine. Radiographic evidence linking tobacco use and lung cancer.
      16436771 The New England journal of medicine, 2006 Jan 26 : 354(4)397
    • McMullan DM, McBride M, Livesay JJ, Dougherty KG, Krajcer Z
      Celiac artery aneurysm: a case report.
      16878636 Texas Heart Institute journal, 2006 : 33(2)235-40 PMCID:PMC1524716
    • DeLaRosa J, Thourani VH, Wheatley GH 3rd, McMullan DM, Karamanoukian RL, Greene MG, Morales DL
      Impact of resident duty hour standards on cardiothoracic residents and program directors.
      16242419 The Annals of thoracic surgery, 2005 Nov. : 80(5)1569-71
    • McMullan DM, Hanley FL, Cohen GA, Portman MA, Riemer RK
      Pulmonary arteriovenous shunting in the normal fetal lung.
      15464334 Journal of the American College of Cardiology, 2004 Oct 6 : 44(7)1497-500
    • McMullan DM, Hanley FL, Riemer RK
      A method for selectively limiting lumen diameter in corrosion casting.
      15121445 Microvascular research, 2004 May : 67(3)215-7
    • Gaissert HA, Casale AS, Creswell LL, Ferguson TB Jr, Fullerton DA, Kernstine KH, McMullan DM, Ring WS, Putnam JB Jr, Society of Thoracic Surgeons Workforce on Clinical Trials.
      Mentoring clinical trials in thoracic and cardiovascular surgery: a new role for the Society of Thoracic Surgeons.
      15111218 The Annals of thoracic surgery, 2004 May : 77(5)1874-5
    • McMullan DM, Wood DE
      Pulmonary carcinoid tumors.
      12973707 Seminars in thoracic and cardiovascular surgery, 2003 July : 15(3)289-300
    • McMullan DM, Wilansky S, Frazier OH
      Ventricular fibrillation in a heterotopic heart transplant recipient.
      12607690 The Annals of thoracic surgery, 2003 Feb. : 75(2)598
    • Malhotra SP, Reddy VM, Thelitz S, He YP, McMullan DM, Hanley FL, Riemer RK
      The role of oxidative stress in the development of pulmonary arteriovenous malformations after cavopulmonary anastomosis.
      12202863 The Journal of thoracic and cardiovascular surgery, 2002 Sept. : 124(3)479-85
    • Black SM, Bekker JM, McMullan DM, Parry AJ, Ovadia B, Reinhartz O, Lakshminrushimha S, Mata-Greenwood E, Steinhorn RH, Fineman JR
      Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow.
      12149501 Pediatric research, 2002 Aug. : 52(2)233-44
    • McMullan DM, Patel V, Radovancevic B, Hochman FL, Frazier OH
      Cytomegalovirus cholecystitis in a heart transplant recipient.
      12072337 Transplantation proceedings, 2002 June : 34(4)1271-2
    • Gutierrez JA, Parry AJ, McMullan DM, Chapin CJ, Fineman JR
      Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow.
      11597919 American journal of physiology. Lung cellular and molecular physiology, 2001 Nov. : 281(5)L1264-70
    • Wedgwood S, McMullan DM, Bekker JM, Fineman JR, Black SM
      Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
      11509453 Circulation research, 2001 Aug 17 : 89(4)357-64
    • McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR
      Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1.
      11158977 American journal of physiology. Heart and circulatory physiology, 2001 Feb. : 280(2)H777-85
    • McMullan DM, Radovaneević B, Jackow CM, Frazier OH, Duvic M
      Cutaneous T-cell lymphoma in a cardiac transplant recipient.
      11678256 Texas Heart Institute journal, 2001 : 28(3)203-7 PMCID:PMC101179
    • McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Kon A, Heidersbach RS, Black SM, Fineman JR
      Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow.
      11082382 Circulation, 2000 Nov 7 : 102(19 Suppl 3)III172-8
    • Beyer EA, McMullan DM, Delgado R, Gregoric I, Radovancevic B, Frazier OH
      Normalization of native heart function years after heterotopic transplantation.
      11093512 The Annals of thoracic surgery, 2000 Nov. : 70(5)1690-1; discussion 1691-2
    • McMullan DM, Beyer EA, Gregoric I, Radovancevic B, Frazier OH
      Left ventricular reduction in a Jehovah's Witness.
      11016342 The Annals of thoracic surgery, 2000 Sept. : 70(3)958-60; discussion 960-1
    • Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR
      Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension.
      10564139 The American journal of physiology, 1999 Nov. : 277(5 Pt 2)H1849-56
    • Petrossian E, Parry AJ, Reddy VM, Akkersdijk GP, McMullan DM, Thompson L, Hendricks-Munoz KD, Hallak H, Hanley FL, Fineman JR
      Endothelin receptor blockade prevents the rise in pulmonary vascular resistance after cardiopulmonary bypass in lambs with increased pulmonary blood flow.
      9918974 The Journal of thoracic and cardiovascular surgery, 1999 Feb. : 117(2)314-23
    • Panis Y, McMullan DM, Emond JC
      Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection.
      9037225 Surgery, 1997 Feb. : 121(2)142-9
    • Lyson T, McMullan DM, Ermel LD, Morgan BJ, Victor RG
      Mechanism of cyclosporine-induced sympathetic activation and acute hypertension in rats.
      8175178 Hypertension (Dallas, Tex. : 1979), 1994 May : 23(5)667-75
    • Dohanich GP, McMullan DM, Cada DA, Mangum KA
      Muscarinic receptor subtypes and sexual behavior in female rats.
      1708147 Pharmacology, biochemistry, and behavior, 1991 Jan. : 38(1)115-24
    • Dohanich GP, McMullan DM, Brazier MM
      Cholinergic regulation of sexual behavior in female hamsters.
      2326327 Physiology and behavior, 1990 Jan. : 47(1)127-31
    • Truong U, McMullan DM
      Percutaneous Catheter-Based Interventions
      In Tran H, le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City, 2008
    • Karamlou T, McMullan DM, Cohen GA
      Truncus Arteriosus
      In Baumgartner WA, Yuh DD, Vricella LA (eds): The John Hopkins Textbook of Cardiothoracic Surgery, 2nd Ed, McGraw-Hill, New York, 2014
    • Bannister L, Blume B, McMullan DM, Petropoulos A, White-Williams C, McMullan DM
      Health Care Delivery
      In Kirk R, Dipchand AI, Rosenthal DN, Kirklin JK (eds): ISHLT Monograph Series Volume 8: ISHLT Guidelines for the Management of Pediatric Heart Failure, Elsevier, Philadelphia, 2014
    • in Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City
      Surgical Treatment of Congenital Heart Disease in Developed Countries
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City, 2008
    • Hoang TK, Shekerdemian LS, McMullan DM, Wilkinson JL
      Characteristic of the Young Infant with Congenital Heart Disease
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developted Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City, 2008
    • Karamlou T, McMullan DM, Baden H, Jeffries H, Cohen GA
      Extracorporeal Membrane Oxygenation in Pediatric Cardiac Care
      In Baumgartner WA, Yuh Dd, Vricella LA (eds): The John Hopkins Textbook of Cardiothoracic Surgery, 2nd Ed, McGraw-Hill, New York, 2014
    • McMullan DM, Elliot MJ, Cohen GA
      ECMO for Infants and Children
      In Gravlee GP, Davis RF, Stammers AH, Ungerleider RM (eds): Cardiopulmonary Bypass Principles and Practice, 3rd ed, Lippincott Williams and Wilkins, Philadelphia, 2007
    • McMullan DM, Cohen GA
      Truncus Arteriosus
      In Baumgartner WA, Yuh DD, Vricella LA (eds): The John Hopkins Manual of Cardiothoracic Surgery, McGraw-Hill, New York, 2007
    • McMullan DM, Pearl J
      New and Developing Technologies for Ventricular Assistance
      In da Cruz EM, Ivy DD, Hraska V, Jagger J (eds): Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, Springer-Verlag, London, 2014
    • Hoang TK, Vu MP, Tran TH, McMullan DM, Shekerdemian LS, Wilkinson JL
      The Burden of Congenital Heart Disease
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City, 2008
    • McMullan DM, Walsh GL
      Pleural Effusions
      In Yang SC, Cameron DE (eds): Current Therapy of Thoracic and Cardiovascular Surgery, Harcourt, Phladelphia, 2004

  • Presentations

    Presentation Title Event Location Date
    Extracorporeal Life Support 35th Annual Pacific Northwest Regional Respiratory Care Conference Seattle, WA Apr 24, 2008
    Trends and Advances in ECMO Department of Surgery Grand Rounds, University of Washington Seattle, WA Apr 7, 2010
    ECMO for Cardiovascular Disease Diagnosis, Management and Prevention of Cardiovascular Disease Symposium Seattle, WA Apr 30, 2011
    Congenital Cardiac Surgery Training and Experience at Seattle Children's Hospital Hospital Grand Rounds, National Pediatric Hospital Skopje, Macedonia Mar 6, 2014
    Extracorporeal Membrane Oxygenation Cardiovascular Surgery Grand Rounds, University of Washington Seattle, WA Oct 17, 2007
    Hands-On ECMO Society of Critical Care Medicine's 43rd Crititcal Care Congress San Francisco, CA Jan 9, 2014
    Aortic Valve Repair Surgery Grand Rounds, Mulago Hospital Kampala, Uganda Mar 15, 2007
    Economics of Mechanical Cardiac Support St. Christopher's Hospital for Children Philadelphia, PA May 20, 2013
    Antibiotic Prophylaxis for Bacterial Endocarditis in Dentistry Seattle Pediatric Dentistry Study Group Seattle, WA Jan 22, 2008
    ECMO in Preterm Neonates 22nd Annual Extracorporeal Life Support Organization Conference Phoenix, AZ Sep 18, 2011
    Mechanical Support of the Postoperative Patient Western Society of Pediatric Cardiology Annual Meeting San Francisco, CA May 9, 2008
    ECLS Costs and Outcomes Vary by Program Size 23rd Annual Extracorporeal Life Support Organization Conference Seattle, WA Sep 14, 2012
    Mass Disaster Medicine: ECLS Support? Fantasy of Fiction 29th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb 27, 2013
    ECPR: A New Approach to Rescuing Patients with Acute Cardiopulmonary Failure Hospital Grand Rounds, Seattle Children's Hospital Seattle, WA Jul 24, 2008
    Nightmare Cases in the Office: Cardiac Arrest and ECPR Western Society of Pediatric Cardiology Annual Meeting Rancho Palos Verdes, CA Apr 9, 2011
    Optimal Surgical Approaches to Neonatal Aortic Stenosis and the Hypoplastic Arch American College of Cardiology Scientific Session San Francisco, CA Mar 10, 2013
    Cardiac ECMO: Indications and Outcomes 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Dental Antibiotic Prophylaxis and Cardiovascular Disease Dental School Grand Rounds, University of Washington Seattle, WA May 16, 2003
    The Avalon Dual Lumen Venovenous Cannula: A Single Institution Experience 26th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb 24, 2010
    ECMO Case Studies - How I Do It 24th Annual Extracorporeal Life Support Organization Conference Philadelphia, PA Sep 21, 2013
    Developing an ECMO Simulation System 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Surgical Education and Practice in Vietnam General Surgery Grand Rounds, University of Texas Houston, TX Jun 4, 2002
    Utilization and Economics of Mechanical Support 9th International Conference of the Pediatric Cardiac Intensive Care Society Miami, FL Dec 12, 2012
    Mechanical Support for Cardiopulmonary Failure Cardiology Grand Rounds, Children's National Medical Center Washington, DC Jan 22, 2007
    ECLS Hands-on Training 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 4, 2014
    Minimizing Perioperative Bleeding on ECMO 1st Annual European Extracorporeal Life Support Organization Conference Rome, Italy May 12, 2012
    Blalock-Taussig Shunt is the Best Choice for a 2.5 kg Patient with Tetralogy of Fallot Western Society of Pediatric Cardiology Annual Meeting Stevenson, WA Jun 9, 2012
    Management of Cardiac and SVC Perforation: To Boldly Go Where No Man has Gone Before 29th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb 27, 2013
    Making the Jump to Centripetal and Quadrox 27th Annual CNMC Symposium on ECMO and Advanced Therapies for Respiratory Failure Keystone, CO Feb 22, 2011
    Splanchnic Artery Aneurysms Cardiovascular Surgery Grand Rounds, Texas Heart Institute Houston, TX Apr 18, 2001
    Beyond Borders: Reflections on International Medical Service in Vietnam 114th Association of American Medical Colleges Annual Meeting Washington, DC Nov 7, 2003
    Extracorporeal Support and VAD Therapy for Children Western Society of Pediatric Cardiology Annual Meeting Scottsdale, AZ Apr 18, 2010
    Supporting the Single Ventricle 1st Annual European Extracorporeal Life Support Organization Conference Rome, Italyl May 12, 2012
    Blunt Thoracic Trauma Cardiothoracic and Vascular Surgery Grand Rounds, University of Texas Houston, TX May 24, 2002
    Thoracic Surgery Training in the United Statees: An Evolving Educational System 14th Annual Meeting of the Asian Society for Cardiovascular Surgery Osaka, Japan Jun 2, 2006
    Pediatric Heart Surgery National Youth Leadership Forum in Medicine Washington, DC Jun 29, 2006
    New Generation Cardiac Assist Devices to Bridge to Cardiac Transplantation 6th Annual Lemire Northwest Symposium on Contemporary Pediatric Critical Care Medicine Seattle, WA Jul 26, 2013
    Cannula Selection and Cannulation Strategies for ECLS 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Cannulation: How to Do It and How Not to Do It - A Pictorial Guide Society of Critical Care Medicine's 43rd Critical Care Congress San Francisco, CA Jan 9, 2014

  • Research Funding

    Grant Title Grantor Amount Award Date
    Seattle Children's Academic Enrichment Fund Award Principal Investigator $50,000 (2 years) 2013 - 2015
    Extracorporeal Life Support Organization Research Award Principal Investigator $7,000 (1 year) 2011 - 2012
    Seattle Children's Academic Enrichment Fund Award Principal Investigator $24,745 (2 years) 2009 - 2011
    Children's National Medical Center Board of Visitors Award Principal Investigator $15,000 (1 year) 2006 - 2007
    NIH Individual National Research Service Award #HL10108-01 Principal Investigator $50,000 (1 year) 1998 - 1999

Overview

Board Certification(s)

Congenital Cardiac Surgery
Thoracic Surgery
Surgery (General Surgery)

Medical/Professional School

University of Texas Southwestern Medical School, Dallas, TX

Residency

University of Washington School of Medicine, Seattle, WA
UT Minimally Invasive Surgery Fellowship, Houston, TX

Fellowship

Royal Children's Hospital, Parkville Vic. 3052, Australia
Texas Heart Institute-Cardiovascular Surgery GME, Houston, TX
University of CA at San Francisco School of Medici, San Francisco, CA

Clinical Interests

His clinical and research interests include complex neonatal heart surgery and improving patient safety during mechanical cardiopulmonary support.

Research Description

The focus of our research is developing improved mechanical extracorporeal life support systems (ECLS). Combined with optimized clinical management protocols, improved ECLS circuit designs provide increased clinical flexibility and patient safety. Current projects include system enhancements that enable decreased anticoagulation, reduced circuit size, and elimination of unnecessary components. Additionally, we are focusing on alternative methods of care provider education to increase quality assurance.

Research Focus Area

Congenital Cardiac Surgery Outcomes, Quality Improvement